2007

  • Laitinen L., Vuorela H., Vuorela P., Marvola M., Kaukonen A.-M. (2007): Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). European Journal of Pharmaceutics and Biopharmaceutics 66:135-145.

  • EEVA M., VUORELA P., TAMMELA P., NYMAN M., OJALA S., FAGERSTEDT K., HAARIO, H. H. VUORELAH. (2007): Development of the CELLOP optimisation model for plant cell cultivation. Biologia Plantarum 51:27-33.

  • Pohjala L., Tammela P., Samanta S.K., Yli-Kauhaluoma J., Vuorela P. (2007): Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays. Analytical Biochemistry 362:221-228.

  • Hamalainen M., Nieminen R., Vuorela P., Heinonen M., Moilanen E. (2007): The anti-inflammatory effects of flavonoids: Genistein, kaempferol, quercetin and daidzein inhibit STAT-1 and NF-kB activation whereas flavone, isorhamnetin, naringenin and pelargonidin inhibit only NF-kB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediators of Inflammation ID Article 45673.

  • Riihimäki L. & Vuorela P. (2007): Tracking of β-Lactoglobulin Binding Compounds with Biofingerprinting Chromatogram Analysis of Natural Products. Natural Product Communications 2:1129-1132.

  • Pohjola L., Hakkola J., Vuorela P. (2007): Predictive value of cellular methods in toxicological evaluation of lead candidates: an insight to hepatotoxicity. Drug Discovery Today: Technologies 4:e97-101.

  • Leppänen, V.M., Tossavainen, H., Permi, P., Lehtiö, L., Rönnholm, G. & Goldman, A., Kilpeläinen, I. & Pihlajamaa, T. (2007) Crystal Structure of the N-terminal NC4 Domain of Collagen IX, a Zinc Binding Member of the Laminin-Neurexin-Sex Hormone Binding Globulin (LNS) Domain Family. J. Biol. Chem. 282:23219-23230.

  • Rantanen, M.K., Lehtiö, L., Rajagopal, L., Rubens, C.E. & Goldman A. (2007) Structure of Streptococcus agalactiaeFEBS J. 274:3128-3137. serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion.

  • Rantanen, M.K., Lehtiö, L., Rajagopal, L., Rubens, C.E. & Goldman A. (2007) Structure of the Streptococcus agalactiae family II inorganic pyrophosphatase at 2.80 Å resolution. Acta Cryst. D63:738-743.

  • Fabrichniy, I.P., Lehtiö, L., Tammenkoski, M., Zyryanov, A.B., Oksanen, E., Baykov, A.A., Lahti, R. & Goldman, A. (2007) A trimetal site and substrate distortion in a family II inorganic pyrophosphatase. J. Biol. Chem. 282:1422-1431.

  • Fabrichniy, I.P., Lehtiö, L., Tammenkoski, M., Zyryanov, A.B., Oksanen, E., Baykov, A.A., Lahti, R. & Goldman, A. (2007) A trimetal site and substrate distortion in a family II inorganic pyrophosphatase. J. Biol. Chem. 282:1422-1431.

  • Römer M, Heinämäki J, Miroshnyk, I, Sandler N, Rantanen J, Yliruusi J. Phase transformations of erythromycin A dihydrate during pelletisation and drying. Eur. J. Pharm. Biopharm. 67:1, (2007) 246-252

  • Tian F, Zhang F, Sandler N., Gordon KC, McGoverin, C, Strachan CJ, Saville DJ, Rades T. Influence of sample characteristics on quantification of carbamazepine hydrate formation by X-ray powder diffraction and Raman spectroscopy. Eur. J. Pharm. Biopharm. 66: 3, (2007) 466-474

  • Savolainen M, Heinz A, Strachan C, Gordon KC, Yliruusi, J, Rades T, Sandler N. Screening for differences in the amorphous state of indomethacin using multivariate visualization Eur J. Pharm. Sci. 30:2 (2007) 113-123

  • Tian F, Sandler N., Aaltonen J, Lang C, Saville DJ, Gordon KC, Strachan CJ, Rantanen J, Rades T. Influence of polymorphic form, morphology and excipient interactions on the dissolution of carbamazepine compacts J. Pharm. Sci. 96:3 (2007) 584-594

  • Tian F., Saville D.J., Gordon K.C., Strachan C.J., Zeitler J.A., Sandler N., Rades T. The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension J. Pharm. Pharmacol. 59:2 (2007) 193-201

  • Räsänen E., Sandler, N. Near infrared spectroscopy in the development of solid dosage forms J. Pharm. Pharmacol. 59:2 (2007):147-159

  • Antikainen O, Kachrimanis K, Malamataris S, Yliruusi J, Sandler, N. Image analysis by pulse coupled neural networks (PCNN)-a novel approach in granule size characterization. J. Pharm. Pharmacol. 59:1 (2007):51-57

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https://www.abo.fi/amnen/farmaci/

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