2021

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• J. Pyrhönen, K.K. Bansal*, R. Bhadane, C.-E. Wilén, O. Salo-Ahen, J.M. Rosenholm*, Molecular dynamics prediction verified by experimental evaluation of the solubility of different drugs in poly(decalactone) for the fabrication of polymeric nanoemulsions. Advanced NanoBiomed Research 2021, https://doi.org/10.1002/anbr.202100072

• Sergey K. Filippov,* Ramil R. Khusnutdinov, Wali Inham, Chang Liu, Christopher J. Garvey, Dmitry O. Nikitin, Irina I. Semina, Shamil F. Nasibullin, Vitaliy V. Khutoryanskiy, Hongbo Zhang, Rouslan I. Moustafine*, "Hybrid Nanoparticles for Haloperidol Encapsulation: Quid Est Optimum?", Polymers, 2021. (accepted)

• Trung-Anh Le, Yong Guo, Jun-Nian Zhou, Jiaqi Yan, Hongbo Zhang, Tan-Phat Huynh*, "Synthesis, characterization and biocompatibility of guar gum-benzoic acid", Int. J. Biol. Macromol, 2021. (accepted)

• Jiahui Zhang, Cheng Ji, Hongbo Zhang, Hui Shi, Fei Mao, Hui Qian, Wenrong Xu, Dongqing Wang, Jianming Pan, Xinjian Fang*, Hélder A. Santos*, Xu Zhang*, “Engineered Neutrophil-Derived Exosome-Like Vesicles for Targeted Cancer Therapy”, Sci. Adv. 2021. (accepted) 

• Zehao Chen, Zhendong Lv, Zhen Zhang, David A. Weitz, Hongbo Zhang, Yuhui Zhang* and Wenguo Cui*. “Advanced microfluidic devices for fabricating multi-structural hydrogel microsphere”, Exploration, 2021. Accepted, Review. 

• S. Jain, A. Vaidya*, P. Kumar Gupta, J.M. Rosenholm, K.K. Bansal*, Antiarthritic Activities of Herbal Isolates: A Comprehensive Review. , 11(11), 1329; https://doi.org/10.3390/coatings11111329

• Yaoyao Wu, Qiang Huang, Junli Wang, Yuhua Dai, Ming Xiao, Yangyang Li*, Hongbo Zhang,*, and Wenbo Xiao*     "The feasibility of targeted magnetic iron oxide nanoagent for noninvasive IgA nephropathy diagnosis", Frontier in Bioengineering and Biotechnology, 2021. Accepted

• Xiaoyu Xu, Shengyi Wang, Yilai Shu, Hongbo Zhang. "Nanoparticle-based inner ear delivery systems  for the treatment of hearing loss", Smart Materials in Medicine, 2021. Accepted, Prospective

• Rui Liu, Annika Smeds, Luyao Wang, Andrey Pranovich, Jarl Hemming, Stefan Willfor, Hongbo Zhang*, Chunlin Xu*. "Fractionation of lignin with decreased heterogeneity: based on a detailed characteristics study of sequentially extracted softwood kraft lignin", ACS Sustainable Chemistry & Engineering, 2021, Accepted. 

• Chang Liu, Xiaoyu Xu, Wenguo Cui, Hongbo Zhang*. "Metal-organic framework (MOF)-based biomaterials in bone tissue engineering", Engineered Regeneration, 2021, Accepted, Prospective.

• M. Suresh Gupta*, T. Pramod Kumar, D. Vishkante Gowda, J.M. Rosenholm, Orodispersible Films: Conception to Quality by Design. Advanced Drug Delivery Reviews 2021, https://doi.org/10.1016/j.addr.2021.113983

• D. Şen Karaman*, A. Pamukçu, M. Baran Karakaplan, O. Kocaoglu, J.M. Rosenholm, Recent advances in the use of mesoporous silica nanoparticles for the diagnosis of bacterial infections. , 16, 6575-6591.

• Chang Liu, Xiaoyu Xu, Oliver Koivisto, Wenhui Zhou, Guillaume Jacquemet, Jessica M. Rosenholm, and Hongbo Zhang*."Improving the Knock-In Efficiency of MOF-Encapsulated CRISPR/Cas9 System through Controllable Embedding Structures", Nanoscale, Accepted.

• Xiaobin Guo, Jiaxiang Bai, Gaoran Ge, Zhidong Wang, Qing Wang, Kai Zheng, Huaqiang Tao, Lirong Zhang, Hongbo Zhang, Dongqing Wang, Xiaogang Zhang, Hongxia Li, Guoqing Pan, Dechun Geng. "Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis", J. Colloid Interface Sci, 2021, 605, 410-424.

• M. Zeng, Y. Shu, M. Parra-Robert, HZ. Zhou, QH. Li, ZF. Rong, D. Desai, W. Jiménez, V. Puntes*, G. Casals*, J.M. Rosenholm*, E. Casals*, Scalable Synthesis of Multicomponent Multifunctional Inorganic Core@Mesoporous Silica Shell Nanocomposites. Materials Science and Engineering: C 2021 128(6):112272, 10.1016/j.msec.2021.112272

• Yuyang Tong, Peixuan Sun, Juanjuan Yong, Hongbo Zhang, Yunxia Huang, Yi Guo, Jinhua Yu, Shichong Zhou, Yulong Wang, Yu Wang, Qinghai Ji, Yuanyuan Wang, Cai Chang. "Radiogenomic Analysis of Papillary Thyroid Carcinoma for Prediction of Cervical Lymph Node Metastasis: A Preliminary Study", Front Oncol. 2021, Accepted.

• Xiaobin Guo, Jiaxiang Bai, Gaoran Ge, Zhidong Wang, Qing Wang, Kai Zheng, Huaqiang Tao, Lirong Zhang, Hongbo Zhang, Dongqing Wang, Xiaogang Zhang, Hongxia Li, Guoqing Pan, Dechun Geng. "Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis", J. Colloid Interface Sci, 2021, 605, 410-424.

• Xiaoyu Xu, Chang Liu, Yonghui Wang, Oliver Koivisto, Junnian Zhou, Yilai Shu, Hongbo Zhang*, "Nanotechnology-based Delivery of CRISPR/Cas9 for Cancer Treatment " Adv. Drug. Deliv. Rev. 2021., Accepted. 

• Yuezhou Zhang, Huaguang Cui, Ruiqi Zhang, Hongbo Zhang* and Wei Huang*, "Nanoparticulation of Prodrug into Medicines for Cancer Therapy", Adv. Sci. 2021, (Accepted) 

• M. Yasir Asghar*, T. Lassila, I. Paatero, V. Dien Nguyen, P. Kronqvist, J. Zhang, A. Slita, C. Löf, Y. Zhou, , K. Törnquist, The stromal-interaction molecule 1 (STIM1) constitutes a promising therapeutic target in thyroid cancer cells. Cellular and Molecular Life Sciences 2021, https://doi.org/10.1007/s00018-021-03880-0

• K.K. Bansal*, E. Özliseli, A. Rosling, J.M. Rosenholm*, Synthesis and Evaluation of Novel Functional Polymers Derived from Renewable Jasmine Lactone for Stimuli-Responsive Drug Delivery. Advanced Functional Materials 2021, https://doi.org/10.1002/adfm.202101998

• N. Prabhakar, J. Merisaari, V. Le Joncour, M. Peurla, D. Şen Karaman, E. Casals, P. Laakkonen, J. Westermarck* and J.M. Rosenholm*, Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions. Cancers 2021, 13(11), 2631; https://doi.org/10.3390/cancers13112631

• P. Trivedi, R. Liu, H. Bi, C. Xu, J.M. Rosenholm, M. Åkerfelt, 3D modeling of epithelial tumors - the synergy between material engineering, high-content imaging and nanotechnology. Int. J. Mol. Sci. 2021, 22, 6225. https://doi.org/10.3390/ijms22126225

• Wei Ji, Xiaodan Li, Mingshu Xiao, Yueyang Sun, Wei Lai, Hongbo Zhang, Hao Pei, and Li Li*, "DNA-Scaffolded Disulfide Redox Network for Programming Drug-Delivery Kinetics", Chem. Eur. J., 2021, (Accepted)  

• Jiaqi Yan, Yichuan Wang, MeiXin Ran, Rawand A. Mustafa, Huanhuan Luo, Jixiang Wang, Jan-Henrik Smått, Jessica Rosenholm, Wenguo Cui, Yong Lu*, Zhenpeng Guan*, Hongbo Zhang*, "Peritumoral Microgel Reservoir for Long-term Light-controlled Trible-synergistic Treatment of Osteosarcoma with Single Ultra-low Dose", Small. 2021, (Accepted) 

• Lei Wu, Wenhui Zhou, Lihua Lin, Anhong Chen, Jing Feng, Xiangmeng Qu*, Hongbo Zhang*, and Jun Yue*, "Delivery of Therapeutic Oligonucleotides in Nanoscale", Bioact. Mater. 2021, (Accepted) 

• Zhen Wang, Yichuan Wang, Jiaqi Yan, Keshi Zhang, Feng Lin, Lei Xiang, Lianfu Deng, Zhenpeng Guan, Wenguo Cui, Hongbo Zhang, "Pharmaceutical Electrospinning and 3D printing scaffold design for bone regeneration", Adv. Drug. Deliv. Rev. 2021., (In press) 

• E.D.H. Mansfield, S.K. Filippov, R. Victor, M.T. Cook, I. Grillo, R. Hoogenboom, A.C. Williams, V.V. Khutoryanskiya, Understanding the temperature induced aggregation of silica nanoparticles decorated with temperature-responsive polymers: Can a small step in the chemical structure make a giant leap for a phase transition? Journal of Colloid and Interface Science 590, 2021, 249-259.

• A. Murmiliuka, S.K. Filippov, O. Rud, P. Košovan, Z. Tošner, A. Radulescu, A. Skandalis, S. Pispas, M. Šlouf, M. Štěpánek, Reversible multilayered vesicle-like structures with fluid hydrophobic and interpolyelectrolyte layers. J. Coll. Interface Sci. 599. 2021, 313-325.

• Feng Zhang, Yiran Zhang, Li Kong, Huanhuan Luo, Yuezhou Zhang, Ermei Mäkilä, Jarno Salonen, Jouni T. Hirvonen, Yueqi Zhu, Yingsheng Cheng, Lianfu Deng, Hongbo Zhang*, Alexander Kros, Wenguo Cui*, Hélder A. Santos*, “Multistage Signal Interactive Nanoparticles Improves Tumor Targeting Through Efficient Nanoparticle-Cell Communications”, Cell Rep. 2021. (accepted)

• M. Parra-Robert, M. Zeng, Y. Shu, G. Fernandez-Varo, M. Perramon, D.  Desai, J.  Chen, D. Guo, X. Zhang, M. Morales-Ruiz, J. Rosenholm, W. Jiménez, V. Puntes, E. Casals, G. Casals, Mesoporous silica coated CeO2 nanozymes with combined lipid-lowering and antioxidant activity induce long-term improvement of the metabolic profile in obese Zucker rats. Nanoscale 2021, https://doi.org/10.1039/D1NR00790D 

• Luca C, Ferrari S, Santucci M, Salo-Ahen OM, Emanuele C, Franchini S, Angela L, Pozzi C, Marverti G, Trande M, Gaia G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Guerrini R, Pacifico S, Luciani R, Genovese F, Stefan H, Silvia A, Santarem N, Cordeiro-da-Silva A, Giovannetti E, Peters G, Pinton P, Rimessi A, Cruciani G, Stroud R, Wade R, Mangani S, D'Arca D, Ponterini G, Costi MP. Disrupters of the Thymidylate Synthase Homodimer Accelerate Its Proteasomal Degradation and Inhibit Cancer Growth. ChemRxiv; 2021. DOI: 10.26434/chemrxiv.14156918.v1.

• S. Manandhar, E. Sjöholm, J. Bobacka, J.M. Rosenholm, K.K. Bansal*, Polymer-Drug Conjugates as Nanotheranostic Agents. J. Nanotheranostics 2021, 2(1), 63-81; https://doi.org/10.3390/jnt2010005

• Huanhuan Luo, Li Kong, Feng Zhang, Chenglong Huang, Jiayi Chen, Hongbo Zhang, Han Yu, Song Zheng, Hongwei Xu, Yiran Zhang, Lianfu Deng, Gang Chen*, Hélder A. Santos*, Wenguo Cui*, “Light-Controlled Nanosystem With Size Flexibility Improves Targeted Retention for Tumor Suppression”, Adv. Funct. Mater. 2021. (accepted) 

• Lu Chen, Liucheng Zhang, Hongbo Zhang, Xiaoming Sun, Dan Liu, Jianming Zhang, Yuguang Zhang*, Liying Cheng*, Hélder A. Santos*, Wenguo Cui*, “Programmable Immune Activating Electrospun Fibers for Skin Regeneration”, Bioact. Mater. 2021. (accepted) 

• Jixing Wang, Lihua Zou, Jingjing Xu, Rong Zhang, Hongbo Zhang*. "Molecularly Imprinted Fluoroprobes Doped with Ag Nanoparticles for Highly Selective Detection of Oxytetracycline in Real Samples", Analytica Chimica Acta. 2021. (accepted) 

• B. Küçüktürkmen & J.M. Rosenholm, Mesoporous silica nanoparticles as carriers for biomolecules in cancer therapy. in "Bio-Nanomedicine for Cancer Therapy" (Springer), 2021, pp 99-120, DOI: 10.1007/978-3-030-58174-9_5; ISBN 978-3-030-58173-2; eBook ISBN 978-3-030-58174-9. Series Vol. 1295, ”Advances in Experimental Medicine and Biology” book series (AEMB, volume 1295).

• A. Mahor, P. Prakash Singh, P. Bharadwaj, N.j Sharma, S. Yadav, J.M Rosenholm, Kuldeep K. Bansal*, Carbon-based nanomaterials for delivery of biologicals & therapeutics: A cutting edge technology. C (Journal of Carbon Research) 2021, 7(1), 19; https://doi.org/10.3390/c7010019

• Zhijie Chen, Feng Zhang, Hongbo Zhang, Liang Cheng, Kaizhe Chen, Jieliang Shen, Jin Qi, Lianfu Deng, Chuan He*, Hélder A. Santos*, Wenguo Cui*, “DNA-Grafted Hyaluronic Acid System with Enhanced Injectability and Biostability for Photo-Controlled Osteoarthritis Gene Therapy”, Adv. Sci. 2021. (accepted) 

• M. Suhail, A. Khan, J.M Rosenholm, M. U. Minhas, P.-C. Wu*, Fabrication and characterization of diclofenac sodium loaded hydrogels of sodium alginate as sustained release carrier. Gels 2021, 7(1), 10; https://doi.org/10.3390/gels7010010

• F. Howaili, E. Özliseli, B. Küçüktürkmen, S. Mahboubeh Razavi, M. Sadeghizadeh* and J.M. Rosenholm*, Stimuli-responsive, plasmonic nanogel for dual delivery of curcumin and photothermal therapy for cancer treatment. Front. Chem. 2021 | https://doi.org/10.3389/fchem.2020.602941

• Junnian Zhou, Tzu-Chen Rautio, Chang Liu, Xiaoyu Xu, Dongqing Wang, Yong Guo, John Eriksson, Hongbo Zhang*, "Delivery of Protein Kinase A by CRISPRMAX and Its Effects on Breast Cancer Stem-Like Properties", Pharmaceutics, 2021, 13(1), 11.

• O.M.H. Salo-Ahen*, I. Alanko, R. Bhadane, A.M.J.J. Bonvin *, R. Vargas Honorato, S. Hossain, A.H. Juffer, A. Kabedev, M. Lahtela-Kakkonen, A. Støttrup Larsen, E. Lescrinier, P. Marimuthu, M. Usman Mirza, G. Mustafa, A. Nunes-Alve*, T. Pantsar, A. Saadabadi, K. Singaravelu, M. Vanmeert, Molecular dynamics simulations in drug discovery and pharmaceutical development. Processes 2021, 9(1), 71; https://doi.org/10.3390/pr9010071

• N. Prabhakar*, I. Belevich, M. Peurla, X. Heiligenstein, H-C. Chang, C. Sahlgren, E. Jokitalo, J.M. Rosenholm, Cell Volume (3D) Correlative Microscopy Facilitated by Intra-cellular Fluorescent Nanodiamonds as Multi-Modal Probes.  Nanomaterials 2021, 11(1), 14; https://doi.org/10.3390/nano11010014