2020

  • Jingyan Gao, Xiaodong Ma, Lirong Zhang, Jiaqi Yan, Huaguang Cui, Yuezhou Zhang, Dongqing Wang, Hongbo Zhang*, "Self-assembled Disulfide Bond Bearing Paclitaxel- Camptothecin Prodrug Nanoparticle for Lung Cancer Therapy", Pharmaceutics, 2020 (Accepted)

  • Öblom, H., Cornett, C., Bøtker, J., Frokjaer, S., Hansen, H., Rades, T., Rantanen, J., Genina, N., 2020. Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing. Int. J. Pharm. 589, 119866. https://doi.org/10.1016/j.ijpharm.2020.119866

  • Oussama Moussaoui*, Rajendra Bhadane, Riham Sghyar, El Mestafa El Hadrami, Soukaina El Amrani, Abdeslem Ben Tama, Youssef Kandri Rodi, Said Chakroune, Outi M. H. Salo-Ahen*, Novel Amino Acid Derivatives of Quinolines as Potential Antibacterial and Fluorophore Agents. Accepted for publication in Scientia Pharmaceutica.

  • Y. Cao, J. Yang, D. Eichin, F. Zhao, D. Qi, L. Kahari, C. Jia, M. Peurla, J.M. Rosenholm, Z. Zhao, S. Jalkanen, Jianwei Li, Self-Synthesizing Nanorods from Dynamic Combinatorial Libraries against Drug Resistant Cancer. Angew. Chem. 2020, https://doi.org/10.1002/ange.202010937

  • Kun Zhang, Xiaoting Cheng, Liping Zhao, Mingqian Huang, Yong Tao, Hongbo Zhang, Jessica M Rosenholm, Min Zhuang, Zheng-Yi Chen, Bing Chen, Yilai Shu. "Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear In Vivo", Molecular Therapy-Methods & Clinical Development, 2020, 18, 511-519.

  • B. Küçüktürkmen & J.M. Rosenholm, Mesoporous silica nanoparticles as carriers for biomolecules in cancer therapy. in "Bio-Nanomedicine for Cancer Therapy" (Springer), ISBN 978-3-030-58173-2; eBook ISBN 978-3-030-58174-9. Series Vol. 1295, ”Advances in Experimental Medicine and Biology” 2020.

  • Xu Zhang*, Hongbo Zhang, Jianmei Gu, Jiayin Zhang, Hui Shi, Hui Qian, Dongqing Wang, Wenrong Xu, Jianming Pan*, Hélder A. Santos*, “Engineered Extracellular Vesicles for Cancer Therapy”, Adv. Mater. 2020.(accepted) (Co-first author)

  • Qiaolin Wei, Hamed Arami,, Hélder A. Santos, Hongbo Zhang, Yangyang Li,, Jian He, Danni Zhong, Daishun Ling, Min Zhou. "Intraoperative Assessment and Photothermal Ablation of the Tumor Margins Using Gold Nanoparticles", Adv. Sci. 2020. Accepted 

  • Jie Shen, Ming Ma, Hongbo Zhang, Huizhu Yu, Fengfeng Xue, Nanjing Hao, Hangrong Chen. "Microfluidics-Assisted Surface Tri-Functionalization of Zeolitic Imidazolate Framework Nanocarrier for Targeted and Controllable Multitherapies of Tumor".  ACS Appl. Mater. Interfaces 2020. (accepted)

  • Mirza MU, Saadabadi A, Vanmeert M, Salo-Ahen OMH et al. Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore-based virtual screening approach. Eur J Pharm Sci. 2020;105537. doi:10.1016/j.ejps.2020.105537

  • Ruoyu Cheng, Flavia Fontana, Junyuan Xiao, Zehua Liu, Patrícia Figueiredo, Mohammad-Ali Shahbazi, Shiqi Wang, Jing Jin, Giulia Torrieri, Jouni T. Hirvonen, Hongbo Zhang, Tongtong Chen, Wenguo Cui*, Yong Lu*, Hélder A. Santos*, “Recombination Monophosphoryl Lipid A Derived Vacosome for the Development of Preventive Cancer Vaccines”, ACS Appl. Mater. Interfaces 2020. (accepted)

  • Ye Liang, Yonghua Wang, Liping Wang, Zhijuan Liang, Dan Li, Xiaoyu Xu, Yuanbin Chen, Xuecheng Yang*, Hongbo Zhang*, HaitaoNiu*. "Self-crosslinkable Chitosan-Hyaluronic Acid Dialdehyde Nanoparticles for CD44-targeted siRNA Delivery to Treat Bladder Cancer". Bioactive Materials, 2020, Accepted.  

  • Z. Gounani, S. Pourianejad, M.A. Asadollahi, R.L. Meyer, J.M. Rosenholm, A. Arpanaei, Polycaprolactone-gelatin nanofibers incorporated with dual antibiotic-loaded carboxyl modified silica nanoparticles. Journal of Materials Science 2020, 55, 17134–17150.

  • M. Rautamo,* K. Kvarnström, M. Sivén, M. Airaksinen, P. Lahdenne and N. Sandler, A Focus Group Study about Oral Drug Administration Practices at Hospital Wards—Aspects to Consider in Drug Development of Age-Appropriate Formulations for Children. Pharmaceutics 2020, 12(2), 109.

  • M. Rautamo,* K. Kvarnström, M. Sivén, M. Airaksinen, P. Lahdenne and N. Sandler, Benefits and Prerequisites Associated with the Adoption of Oral 3D-Printed Medicines for Pediatric Patients: A Focus Group Study among Healthcare Professionals. Pharmaceutics 2020, 12(3), 229.

  • Minghua Yao, Xiaojing Shi, Changjing Zuo, Ming Ma,* Lu Zhang, Hongbo Zhang, Xin Li, Guo-Yuan Yang, Yaohui Tang,* Rong Wu.* "Engineering of SPECT/Photoacoustic Imaging/Antioxidative-Stress Triple-Function Nanoprobe for Advanced Mesenchymal Stem Cell Therapy of Cerebral Ischemia".  ACS Appl. Mater. Interfaces 2020

  • K.K. Bansal*, E. Özliseli, G.K. Saraogi and J.M. Rosenholm, Assessment of Intracellular Delivery Potential of Novel Sustainable Poly(δ-decalactone)-Based Micelles. Pharmaceutics 2020, 12(8), 726; https://doi.org/10.3390/pharmaceutics12080726

  • P.K. Raghu, K.K. Bansal, P. Thakor, V. Bhavana, J. Madan, J.M. Rosenholm and N. Kumar Mehra, Evolution of Nanotechnology in Delivering Drugs to Eyes, Skin and Wounds via Topical Route. Pharmaceuticals 2020, 13(8), 167; https://doi.org/10.3390/ph13080167

  • Guicai Li, Qi Han, Liling Zhang, Panjian Lu, Yuezhou Zhang, Shiyu Chen, Ping Zhang, Luzhong Zhang, Wenguo Cui, Hongkui Wang, Hongbo Zhang*. "Construction of Dual-Biofunctionalized Chitosan/Collagen Scaffolds for Simultaneous Neovascularization and Nerve Regeneration". Research 2020, Accepted.

  • Jiaqi Yan, Chang Liu, Qiwei Wu, Junnian Zhou, Xiaoyu Xu, Lirong Zhang, Dongqing Wang, Fan Yang, Hongbo Zhang. "Mineralization of pH sensitive Doxorubicin Prodrug in ZIF-8 to Enable the Target Delivery to Solid Tumors" Analytical Chemistry, 2020 Accepted.

  • Z. Gounani, D. Şen Karaman, A.P. Venu, F. Cheng, J.M. Rosenholm, Coculture of P. aeruginosa and S. aureus on cell derived matrix - an in vitro model of biofilms in infected wounds. Journal of Microbiological Methods 2020, 175, 105994.

  • Emilia Palo, Hongbo Zhang, Mika Lastusaari, Mikko Oskari Salomäki.  "Nanometer-Thick Ion-Selective Polyelectrolyte Multilayer Coatings to Inhibit the Disintegration of Inorganic Upconverting Nanoparticles" ​ACS Appl. Nano Mater. 2020​, Accepted.

  • Yang Ye,*, Jian He,*, Yue Qiao,*, Yuchen Qi,*, Hongbo Zhang,*, Helder Santos*, Danni Zhong, Wanlin Li, Shiyuan Hua, Wei Wang, Andrzej Grzybowski, Ke Yao,# and Min Zhou# "Mild temperature photothermal assisted anti-bacterial and anti-inflammatory nanosystem for synergistic treatment of post-cataract surgery endophthalmitis". Theranostics 2020, Accepted.

  • K.K. Kesari*, A. Dhasmana, S. Shandilya, N. Prabhakar, A. Shaukat, J. Dou, J.M. Rosenholm, T. Vuorinen*, J. Ruokolainen*, Plant-Derived Natural Biomolecule Picein Attenuates Menadione Induced Oxidative Stress on Neuroblastoma Cell Mitochondria. Antioxidants. 2020, 9(6), 552; https://doi.org/10.3390/antiox9060552

  • A. Kumar Rajora*, D. Ravishankar, H. Zhang, J.M. Rosenholm*, Recent advances and impact of nanoformulations of chemo- and antiangiogenesis for combination cancer therapy. Pharmaceutics 2020, 12(6), 592; https://doi.org/10.3390/pharmaceutics12060592

  • J. Zhang & J.M. Rosenholm, Molecular and nanoscale engineering of porous silica particles for drug delivery. Book chapter in: “Nanoengineered Biomaterials for advanced drug delivery, 1st Edition”, Editor: M. Mozafari © Elsevier 2020, Paperback ISBN:  9780081029855.

  • Chang Liu; Xiaoyu Xu; Junnian Zhou; Jiaqi Yan; Dongqing Wang; Hongbo Zhang*. "Redox-responsive Tumor Targeted Dual-drug Loaded Biocompatible Metal-organic Frameworks Nanoparticles for Enhancing Anticancer Effects", BMC Mater. 2020 (Accepted).

  • Xiaoyu Xu; Oliver Koivisto; Chang Liu; Daqi Wang; Junnian Zhou; Mitro Miihkinen; Guillaume Jacquemet; Jessica M. Rosenholm*; Yilai Shu*; Hongbo Zhang*.  "Effective delivery of the CRISPR/Cas9 system enabled by functionalized mesoporous silica nanoparticles for GFP-tagged paxillin knock-in", Adv Ther, 2020, https://doi.org/10.1002/adtp.202000072

  • D. Pardhi, D. Şen Karaman, J. Timonen, W. Wu, Q. Zhang, S. Satija, M. Mehta, N. Charbe, P. McCarron, M. Tambuwala, H.A. Bakshi, P. Negi,  A.A Aljabali,  K. Dua, D.K Challappan, A. Behera , K. Pathak, R.B. Watharkar, J. Rautio, J.M. Rosenholm, Anti-bacterial effects of inorganic nanomaterials and their antimicrobial peptide conjugates against resistant and non-resistant pathogens. International Journal of Pharmaceutics 2020, DOI: 10.1016/j.ijpharm.2020.119531

  • Alamri MA, Tahir ul Qamar M, Mirza MU, Bhadane R, Alqahtani SM, Muneer I, Froeyen M, Salo-Ahen OMH: Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro. J Biomol Struct Dyn; DOI:10.1080/07391102.2020.1782768.

  • Kawthar Mohamed, Eduardo Rodríguez-Román, Farzaneh Rahmani, Hongbo Zhang, Mariya Ivanovska, Sara A. Makka, Musa Joya, Rangarirai Makuku, Md Shahidul Islam, Nesrine Radwan, Laila Rahmah, Rayan Goda, Sunny O. Abarikwu, Mujtaba Shaw, Samaneh Zoghi, Sevan Irtsyan , Irene Ling, Orsolya Cseprekal, Attig-Bahar Faten, Esra Hazar Sayar, Chagajeg Soloukey, Giulia Grancini, Nima Rezaei. International Efforts to Save Healthcare Personnel during COVID-19. Acta Biomedica Atenei Parmensis, 2020, 3/20 (September) , COVID-19 UPDATE section. 

  • E. Özliseli, D. Ṣen Karaman*, S. Chakraborti*, A. Slita, M. Parikainen, C.M. Sahlgren, J.M. Rosenholm, Rational evaluation of human serum albumin coated mesoporous silica nanoparticles for xenogenic-free stem cell therapies. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2020, 600, 124945.

  • Yunzhan Li, Zehua Liu, Li Li, Wenhua Lian, Yaohui He, Elbadry Khalil, Ermei Mäkilä, Wenzhong Zhang, Giulia Torrieri, Xueyan Liu, Jingyi Su, Yuanming Xiu, Flavia Fontana, Jarno Salonen, Jouni Hirvonen, Wen Liu, Hongbo Zhang*, Hélder A. Santos*, Xianming Deng*, “Tandem-Mass-Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses Under Diseased Condition”, Adv. Sci. 2020. (accepted)

  • Kawthar Mohamed, Eduardo Rodríguez-Román, Farzaneh Rahmani, Hongbo Zhang, Mariya Ivanovska, Sara A. Makka, Musa Joya, Rangarirai Makuku, Md Shahidul Islam, Nesrine Radwan, Laila Rahmah, Rayan Goda, Sunny O. Abarikwu, Mujtaba Shaw, Samaneh Zoghi, Sevan Irtsyan, Irene Ling, Orsolya Cseprekal, Attig-Bahar Faten, Esra Hazar, Chagajeg Soloukey Tbalvandany, Giulia Grancini, Nima Rezaei, "Borderless collaboration is needed for COVID-19; a disease that knows no borders", Infection Control & Hospital Epidemiology, 2020, 1-7

  • J. Rosenholm & T. Näreoja, Silica Nanoparticles for Diagnosis, Imaging and Theranostics. Invited book chapter, in book “Handbook of Materials for Nanomedicine - Lipid-Based and Inorganic Nanomaterials”, Edited By Vladimir Torchilin, Pan Stanford Publishing 2020. https://www.taylorfrancis.com/books/e/9781003045076/chapters/10.1201/9781003045076-9

  • K.K. Bansal* and J.M. Rosenholm, Synthetic polymers from renewable feedstocks: An alternative to fossil-based materials in biomedical applications. Therapeutic Delivery 2020 , https://doi.org/10.4155/tde-2020-0033

  • Benkherouf AY, Logrén N, Somborac T, Kortesniemi M, Soini SL, Yang B, Salo-Ahen OMH, Laaksonen O, Uusi-Oukari M. Hops compounds modulatory effects and 6-prenylnaringenin dual mode of action on GABAA receptors. Eur J Pharmacol. 2020 Jan 27;873:172962. doi: 10.1016/j.ejphar.2020.172962. Epub ahead of print. PMID: 32001220.

  • D. Şen Karaman*, U. Kürşat Ercan, E. Bakay, N. Topaloğlu, J.M. Rosenholm*, Evolving technologies and strategies for combating antibacterial resistance in the advent of the post-antibiotic era. Advanced Functional Materials 2020 (invited progress report) DOI: 10.1002/adfm.201908783

  • E. Rosqvist, E. Niemelä, J. Frisk, H. Öblom, R. Koppolu, H. Abdelkader, D. Soto Véliz, M. Mennillo, A. P. Venu, P. Ihalainen, M. Aubert, N. Sandler, C.-E. Wilén, M. Toivakka, J. E. Eriksson, R. Österbacka  and  J. Peltonen, A low-cost paper-based platform for fast and reliable screening of cellular interactions with materials. Journal of Materials Chemistry B 2020, 8, 1146-1156.

  • Liucheng Zhang, Yi Xiang, Hongbo Zhang, Liying Cheng, Xiyuan Mao, Ning An, Lu Zhang, Jinxiong Zhou, Lianfu Deng, Yuguang Zhang*, Xiaoming Sun*, Hélder A. Santos*, Wenguo Cui*, “Biomimetic 3D-Self-Forming Approach For Microvascular Scaffolds”, Adv. Sci. 2020. (accepted)

  • Denesyuk AI, Johnson MS, Salo-Ahen OMH, Uversky VN, Denessiouk K: NBCZone: Universal three-dimensional construction of eleven amino acids near the catalytic nucleophile and base in the superfamily of (chymo)trypsin-like serine fold proteases. Int. J. Biol. Macromol. 153: 399-411, 2020. doi: 10.1016/j.ijbiomac.2020.03.025.

  • Jiaqi Yan, Xiaoyu Xu, Junnian Zhou, Chang Liu, Lirong Zhang, Dongqing Wang, Fan Yang, Hongbo Zhang*, ” Fabrication of a pH/redox-triggered mesoporous silica-based nanoparticle with microfluidics for anti-cancer drugs doxorubicin and paclitaxel co-delivery”, ACS Applied Bio Materials, 2020 (Accepted).

  • Jian He, Yue Qiao, Hongbo Zhang, Jun Zhao,Wanli Li, Tingting Xie, Danni Zhong, Qiaolin Wei, Shiyuan Hua, Yinhui Yu, Ke Yao, Hélder A. Santos*, Min Zhou*, “Gold-Silver Nanoshells Promote Wound Healing from Drug-Resistant Bacteria Infection and Enable Monitoring via Surface-Enhanced Raman Scattering Imaging”, Biomaterials 2020. (accepted)

  • E. Niemelä, D. Desai, R. Niemi, M. Doroszko, E. Özliseli, K. Kemppainen, N. Rahman, C. Sahlgren, K. Törnquist, J.E. Eriksson and J.M. Rosenholm, Nanoparticles carrying fingolimod and methotrexate enables targeted induction of apoptosis and immobilization of invasive thyroid cancer. European Journal of Pharmaceutics and Biopharmaceutics 2020, https://doi.org/10.1016/j.ejpb.2019.12.015

  • K.K. Bansal *, D.K. Mishra, A. Rosling, J.M Rosenholm*, Therapeutic Potential of Polymer Coated Mesoporous Silica Nanoparticles. Applied Sciences 2020, 10(1), 289; https://doi.org/10.3390/app10010289

  • H Wickström, R Koppolu, E Mäkilä, M Toivakka, N Sandler, Stencil Printing—A Novel Manufacturing Platform for Orodispersible Discs. Pharmaceutics 12 (1), 2020, 33. DOI: https://doi.org/10.3390/pharmaceutics12010033

  • A.H. Ibrahim, J.-H. Smått, N.P. Govardhanam, H.M. Ibrahim, H.R. Ismael, M.I. Afouna, A.M. Samy, J.M. Rosenholm, Formulation and optimization of drug-loaded mesoporous silica nanoparticle-based tablets to improve the dissolution rate of the poorly water-soluble drug silymarin. European Journal of Pharmaceutical Sciences 2020, 142, 105103 https://doi.org/10.1016/j.ejps.2019.105103

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