2017
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H. Wickström, E. Hilgert, J.O. Nyman, D. Desai, D. Sen Karaman, T. de Beer, N. Sandler, Inkjet printing of drug loaded mesoporous silica nanoparticles – a platform for drug development. Molecules 2017, 22(11), 2020; doi:10.3390/molecules22112020.
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J. Holländer, R. Hakala, J. Suominen, N. Moritz, J. Yliruusi, N. Sandler, 3D printed UV light cured polydimethylsiloxane devices for drug delivery. International Journal of Pharmaceutics 2017, DOI: 10.1016/j.ijpharm.2017.11.016
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E. Yildir,* E. Sjöholm, M. Preis, P. Trivedi, J. Trygg, P. Fardim & N. Sandler, Investigation of dissolved cellulose in development of buccal discs for oromucosal drug delivery. Pharmaceutical Development and Technology 2017, DOI: 10.1080/10837450.2017.1397163
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N. Prabhakar, M. Peurla, S. Koho, T. Deguchi, T. Näreoja, H-C. Chang, J. Rosenholm* and P. Hänninen, STED and confocal - TEM correlative microscopy leveraging nanodiamonds as intracellular dual-contrast markers. Small 2017, DOI: 10.1002/smll.201701807
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N. Prabhakar, A. Määttänen, J. Peltonen, P. Hänninen, M. Peurla,* J.M Rosenholm, Gold nanoparticle printed coverslips to facilitate fluorescence-TEM correlative microscopy. Microscopy 2017, DOI: 10.1093/jmicro/dfx118
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B. Törngren, S. Sandén, J.O. Nyman, A. Tiihonen, H. Jiang, J. Ruokolainen, J. Halme, R. Österbacka, J-H. Smått, Minimizing Structural Deformation of Gold Nanorods in Plasmon-Enhanced Dye-sensitized Solar Cells. Journal of Nanoparticle Research 2017, 19(11) DOI: 10.1007/s11051-017-4062-9
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M. Krishnamoorthy, D. Li, A. Sharili, T. Gulin-Safraz, J.M. Rosenholm, J. Gautrot, The Solution Conformation of Polymer Brushes Determines their Interactions with DNA and Transfection Efficiency. M. Krishnamoorthy, D. Li, A. Sharili, T. Gulin-Safraz, J.M. Rosenholm, J. Gautrot, The Solution Conformation of Polymer Brushes Determines their Interactions with DNA and Transfection Efficiency. Biomacromolecules 2017, DOI: 10.1021/acs.biomac.7b01175
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J. Liu, D. Şen Karaman, J. Zhang, , X. Guo, K. Cai, NIR Light-Activated Dual-Modality Cancer Therapy Mediated by Photochemical Internalization of Porous Nanocarriers with Tethered Lipid Bilayer. Journal of Materials Chemistry B 2017, DOI: 10.1039/C7TB02095C
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Xiangmeng Qu, Min Li, Hongbo Zhang, Chenglie Lin, Fei Wang, Mingshu Xiao, Yi Zhou, Jiye Shi, Ali Aldalbahi, Hao Pei, Hong Chen, Li Li. Real-Time Continuous Identification of Greenhouse Plant Pathogens Based on Recyclable Microfluidic Bioassay System. ACS Applied Materials & Interfaces 2017, 9 (37), pp 31568–31575
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M. Palo, J. Holländer, J. Suominen, J. Yliruusi & N. Sandler, 3D printed drug delivery devices: perspectives and technical challenges. Expert Review of Medical Devices 2017, DOI: 10.1080/17434440.2017.1363647
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Aho, Johanna; Halme, Amanda; Boetker, Johan; Water, Jorrit Jeroen; Bohr, Adam; Sandler, Niklas; Rantanen, Jukka; Baldursdottir, Stefania; The effect of HPMC and MC as pore formers on the rheology of the implant microenvironment and the drug release in vitro. Carbohydrate polymers 2017, 177, 433-442.
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C. Weinberger, S. Ren, M. Hartmann, T. Wagner, D. S. Karaman, J.M. Rosenholm, M. Tiemann, Bimodal Mesoporous CMK 5 Carbon: Selective Pore Filling with Sulphur and SnO2 for Lithium Battery Electrodes. ACS Applied Nano Materials 2017, DOI: 10.1021/acsanm.7b00307
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Hongbo Zhang, Xiangmeng Qu, Hong Chen, Ruihua Ding, Dong Chen, Weixia Zhang, Xu Zhang, Hao Pei, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Fabrication of Calcium Phosphate-based Nanocomposites Containing DNA Origami, Gold nanorods and Drugs for Synergistic Anticancer Applications”, Adv. Healthcare Mater. 2017. (accepted)
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Sandler, Niklas; Ihalainen, Petri; Khinast, Johannes; Rantanen, Jukka; Perspectives of Printing Technologies in Continuous Drug Manufacturing. Continuous Manufacturing of Pharmaceuticals 2017, 525-549.
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Tomás Bauleth-Ramos, Mohammad-Ali Shahbazi*, Dongfei Liu, Flavia Fontana, Alexandra Correia, Patrícia Figueiredo, Hongbo Zhang, João Pedro Martins, Jouni T. Hirvonen, Pedro Granja, Bruno Sarmento*, Hélder A. Santos*, “Nutlin-3a and Cytokine co-loaded Spermine-modified Acetalated Dextran Nanoparticles for Cancer Chemo-immunotherapy”, Adv. Funct. Mater. 2017. (accepted)
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Raijada, Dhara; Arnfast, Lærke; Bond, Andrew D; Aho, Johanna; Bøtker, Johan; Sandler, Niklas; Rantanen, Jukka; Dehydration of nitrofurantoin monohydrate during melt extrusion. Crystal Growth & Design 2017 (in press)
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Dongfei Liu*, Hongbo Zhang, Flavia Fontana, Jouni T. Hirvonen, Hélder A. Santos*, “Current Developments and Applications of Microfluidic Technology Toward Clinical Translation of Nanomedicines”, Adv. Drug Deliv. Rev. 2017. (Invited Review) (in press)
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Varan, Cem; Wickström, Henrika; Sandler, Niklas; Aktaş, Yeşim; Bilensoy, Erem; Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration. International Journal of Pharmaceutics 2017, 15, 701-713.
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Henni Auvinen, Hongbo Zhang, Nonappa, Alisa Kopilow, Elina H. Niemelä, Sami Nummelin, Alexandra Correia, Hélder A. Santos, Veikko Linko*, Mauri A. Kostiainen*, “Protein Coating of DNA Nanostructures for Enhanced Delivery, Stability and Immunocompatibility”, Adv. Healthcare Mater. 2017. (in press)
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M. Preis & J.M. Rosenholm, "Printable nanomedicines: the future of customized drug delivery?" Therapeutic Delivery (editorial) 2017, https://doi.org/10.4155/tde-2017-0051
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D. Desai, J. Zhang, J. Sandholm, J. Lehtimäki, T. Grönroos, J. Tuomela*, J.M. Rosenholm*, Lipid bilayer-gated mesoporous silica nanocarriers for tumor targeted delivery of zoledronic acid in vivo. Molecular Pharmaceutics 2017, DOI: 10.1021/acs.molpharmaceut.7b00519O.
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Vakili, Hossein; Wickström, Henrika; Desai, Diti; Preis, Maren; Sandler, Niklas; Application of a handheld NIR spectrometer in prediction of drug content in inkjet printed orodispersible formulations containing prednisolone and levothyroxine, International journal of pharmaceutics 2017, 524, 414-423.
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A. Maleki, H. Kettiger, A, Schoubben, J.M. Rosenholm*, V. Ambrogi*, M. Hamidi*, Mesoporous Silica Materials: From Physico-Chemical Properties to Enhanced Dissolution of Poorly Water-Soluble Drugs (Review). Journal of Controlled Release 2017, https://doi.org/10.1016/j.jconrel.2017.07.047
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I. Paatero, E. Casals, R. Niemi, E. Özliseli, J.M. Rosenholm, C. Sahlgren, Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes. Scientific Reports 2017, DOI: 10.1038/s41598-017-09312-z
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C. Sahlgren, A. Meinander, H. Zhang, F. Cheng, M. Preis, C. Xu, T. Salminen, D. Toivola, D. Abankwa, D. Şen Karaman, O.M.H. Salo-Ahen, R. Österbacka, J.E. Eriksson, S. Willför, I. Petre, J. Peltonen, R. Leino, M. Johnson, J. Rosenholm, N. Sandler, Tailored approaches in drug development and diagnostics – from molecular design to biological model systems (Review). Advanced Healthcare Materials, DOI: 10.1002/adhm.201700258 (in press).
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Sarmanova, S. Burikov, S. Dolenko, E. von Haartman, D.S. Karaman, I. Isaev, K. Laptinskiy, J. Rosenholm and T. Dolenko. Neural Network Classification Method for Solution of the Problem of Monitoring the Removal of the Theranostics Nanocomposites from an Organism. Advances in Intelligent Systems and Computing (Springer), 2017, v.636, pp.173-179. DOI: 10.1007/978-3-319-63940-6_24
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N. Prabhakar, M.H. Khan, M. Peurla, H.-C. Chang, P.E. Hänninen, J.M. Rosenholm, Intracellular trafficking of fluorescent nanodiamonds and regulation of their cellular toxicity. ACS Omega 2017, 2 (6), 2689–2693. DOI: 10.1021/acsomega.7b00339
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Dongfei Liu,* Hongbo Zhang, Flavia Fontana, Jouni T. Hirvonen, Hélder A. Santos*, “Microfluidic-Assisted Fabrication of Carriers for Controlled Drug Delivery”, Lab Chip 2017. (Review) (in press
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Xiangmeng Qu, Fan Yang, Hong Chen, Jiang Li, Hongbo Zhang, Guo-Jun Zhang, Li Li, Lihua Wang, Shiping Song, Yang Tian, and Hao Pei*. "Bubble-Mediated Ultrasensitive Multiplex Detection of Metal Ions in Three-Dimensional DNA Nanostructure-Encoded Microchannels". ACS Appl. Mater. Interfaces 2017.
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Nolvi, A; Viitala, T; Pérez, A García; Sandler, N; Hæggström, E; Bermudez, C; Artigas, R; Kassamakov, I; Round Robin test on bio-imaging transfer standard for 3D optical profilers, Proc. of SPIE 2017 Vol. 10110, 101100M-1
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Agne Janoniene, Zehua Liu, Lina Baranauskiene, Ermei Mäkilä, Ming Ma, Jarno Salonen, Jouni Hirvonen, Honbgo Zhang*, Vilma Petrikaite*, Hélder A. Santos*, “A Versatile Carbonic Anhydrase IX Targeting Ligand Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging”, ACS Appl. Mater. Interfaces 2017.
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Kari Kopra, Arjan J. van Adrichem, Outi M. H. Salo-Ahen, Juha Peltonen, Krister Wennerberg, and Harri J. Härmä. High-Throughput Dual Screening method for Ras Activities and Inhibitors. Anal. Chem. 89 (8), pp 4508–4516, 2017. DOI: 10.1021/acs.analchem.6b04904.
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Feng Zhang, Alexandra Correia, Ermei M. Mäkilä, Wei Li, Jarno J. Salonen, Jouni Hirvonen, Hongbo Zhang*, Hélder A. Santos*, “Receptor-Mediated Surface Charge Inversion Platform Based on Porous Silicon Nanoparticles for Efficient Cancer Cell Recognition and Combination Therapy”, ACS Appl. Mater. Interfaces 2017. (in press)
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T. Näreoja*, J.M. Rosenholm, U. Lamminmäki, P.E. Hänninen, Super-sensitive time-resolved fluoroimmunoassay for thyroid-stimulating hormone utilizing europium(III) nanoparticle labels achieved by protein corona stabilization, short binding time and serum preprocessing. Anal. Bioanal. Chem. 2017 DOI: 10.1007/s00216-017-0284-z.
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Hongbo Zhang*, Dongfei Liu, Liang Wang, Zehua Liu, Runrun Wu, Agne Janoniene, Ming Ma, Guoqing Pan, Lina Baranauskiene, Linlin Zhang, Wenguo Cui, Vilma Petrikaite, Daumantas Matulis, Hongxia Zhao, Jianming Pan*, Hélder A. Santos*, “Microfluidic Encapsulation of Prickly Zinc-doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy”, Adv. Healthcare Mater. 2017.
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D. Şen Karaman*, S. Manner, A. Fallarero, J.M. Rosenholm, Current Approaches for Exploration of Nanoparticles as Antibacterial Agents. Dr. Ranjith Kumavath (Ed.), InTech, 2017, ”Antibacterial Agents," ISBN 978-953-51-3200-4. Available from: https://www.intechopen.com/books/antibacterial-agents/current-approaches-for-exploration-of-nanoparticles-as-antibacterial-agents
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A.K.O. Åslund*, E. Sulheim, S. Snipstad, E. von Haartman, H. Baghirov, N. Starr, M. Kvåle Løvmo, S. Lelú, D. Scurr, C. de Lange Davies, R. Schmid, Ý. Mørch, Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles. Mol. Pharmaceutics 2017 DOI: 10.1021/acs.molpharmaceut.6b01085
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Balasubramanian V*, Coreia A, Zhang H, Fontana F, Mäkilä E, Salonen J, Hirvonen J, Santos HA*, “Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-like Functions”, Adv. Mater. 2017. (accepted)
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Palo M, Kogermann K, Laidmäe I, Meos A, Preis M, Heinämäki J, and Sandler, N. Development of Oromucosal Dosage Forms by Combining Electrospinning and Inkjet Printing. Molecular Pharmaceutics 2017, 14, 808-820,
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Naudin C, Schumski A, Salo-Ahen OM, Herwald H, Smeds E. A rapid method for selecting suitable animal species for studying pathogen interactions with plasma protein ligands in vivo. Microb Biotechnol. 2017 Feb 7. doi: 10.1111/1751-7915.12601.
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Sun X, Lang Q, Zhang H, Cheng L, Zhang Y, Pan G, Zhao X, Yang H, Zhang Y, Santos HA, Cui W, Cell Scaffolds: Electrospun Photocrosslinkable Hydrogel Fibrous Scaffolds for Rapid in Vivo Vascularized Skin Flap Regeneration. Adv. Funct. Mater. 2017, 27(2).
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Preis M, Breitkreutz J. Pediatric Drug Development and Dosage Form Design. AAPS PharmSciTech 2017;18(2):239-40.
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M. Kaasalainen, V. Aseyev, E. von Haartman, D. Sen Karaman, E. Mäkilä, H. Tenhu, J. Rosenholm and J. Salonen Size, stability and porosity of mesoporous nanoparticles: from dry state towards colloidal characterisation. Nanoscale Research Letters 2017, 12:74 DOI 10.1186/s11671-017-1853-y
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Preis M and Öblom H. 3D-Printed Drugs for Children? Are We Ready Yet? AAPS PharmSciTech 2017;18(2):303-8.
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S. Manner, D. M Goeres, M. Skogman, P. Vuorela, A. Fallarero. Prevention of Staphylococcus aureus biofilm formation by antibiotics in 96-Microtiter Well Plates and Drip Flow Reactors: critical factors influencing outcomes. Scientific Reports, in press.
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K. Lingeshwar Reddy, N. Prabhakar, R. Arppe, J.M. Rosenholm and V. Krishnan. Microwave assisted one step synthesis of hydrophilic NaYF4:Yb/Er upconversion nanoparticles and their application in cancer cell imaging. Materials Science 2017, DOI: 0.1007/s10853-017-0809-z
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T. Näreoja, T. Deguchi, S. Christ, R. Peltomaa, N. Prabhakar, E. Fazeli, N. Perälä, J. Rosenholm, R. Arppe, T. Soukka, M. Schäferling, Ratiometric sensing and imaging of intracellular pH using polyethyleneimine-coated photon upconversion nanoprobes. Analytical Chemistry 2017, 89 (3), 1501–1508.
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H.Wickström, J.O. Nyman, M.Indola, H.Sundelin, L.Kronberg, M.Preis, J.Rantanen, N. Sandler, Colorimetry as Quality Control Tool for Individual Inkjet-Printed Pediatric Formulations. AAPS PharmSciTech 2017, 18, 293-302.